LongevityMap Gene
Gene details
- HGNC symbol
- ADGRL4
- Aliases
- ETL; ELTD1; KPG_003
- Common name
- adhesion G protein-coupled receptor L4
- Description
- Cytogenetic Location
- 1p31.1
- UCSC Genome Browser
- View 1p31.1 on the UCSC genome browser
- OMIM
- 616419
- Ensembl
- ENSG00000162618
- UniProt/Swiss-Prot
- AGRL4_HUMAN
- Entrez Gene
- 64123
- UniGene
- 132314
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
- Caenorhabditis elegans
- lat-1
- Caenorhabditis elegans
- lat-2
- Danio rerio
- adgrl4
- Mus musculus
- Adgrl4
- Rattus norvegicus
- Adgrl4
Studies (1)
Significant/Non-significant: 0/1
- Longevity Association
- Non-significant
- Population
- European
- Study Design
- Meta-analysis of genome-wide association studies of survival and survival free of major disease or death. In total, there were 25,007 participants over 55 years of age and followed-up for over 10 years for mortality and over 8 years for event-free survival.
- Conclusions
- No SNP was significantly associated with time to event after correcting for multiple testing, but 8 independent SNPs predicted event-free survival at a suggestive threshold
- Indentifier
- rs11162963
- Reference