LongevityMap variant

Entry Details

Longevity Association
Significant
Population
American (Caucasian)
Study Design
Genome-wide association study using 1,471 genotyped participants from the Framingham Heart Study, of which 1,173 individuals had known lifespans, plus 517 individuals from the Offspring cohort for validating connections between longevity and genetic variants
Conclusions
A total of 27 SNPs, including in CDH4, SVEP1, CACNA1C, CARS, STK24, C7orf50, PARVG, NCAM2, PPP2R2C, NLRC5, BTBD9, RAC2, TGFA, KIAA0649, ABCC4, CLSTN2, FAM19A5 and RUNX3, were identified at the intersection of various statistical procedures
Identifier
rs10256972
Cytogenetic Location
7p22.3
UCSC Genome Browser
View 7p22.3 on the UCSC genome browser

Gene details

HGNC symbol
C7orf50
Aliases
YCR016W 
Common name
chromosome 7 open reading frame 50 
Description
OMIM
Ensembl
ENSG00000146540
UniProt/Swiss-Prot
CG050_HUMAN
Entrez Gene
84310
UniGene
653258
HapMap
View on HapMap

Homologs in model organisms

Danio rerio
567594
Mus musculus
3110082I17Rik
Rattus norvegicus
LOC498154

References

Yashin et al. (2012)

Other variants which are also part of this study