LongevityMap variant

Entry Details

Longevity Association
Significant
Population
Italian
Study Design
Polymorphisms A/C (Asp/Thr) transition at 647 nt position and A/G (Lys/Arg) transition at 1,245 nt position were examined in 251 old and very old females
Conclusions
For the +647 polymorphism significant differences were observed between old and very old females. Females with Asp/Asp genotype display reduced IL-6 plasma concentrations.
Identifier
647A/C
Cytogenetic Location
16q13
UCSC Genome Browser
View 16q13 on the UCSC genome browser

Gene details

HGNC symbol
MT1A
Aliases
MT1; MTC; MT1S 
Common name
metallothionein 1A 
Description
Other longevity studies of this gene
2
OMIM
156350
Ensembl
ENSG00000205362
UniProt/Swiss-Prot
MT1A_HUMAN
Entrez Gene
4489
UniGene
655199
HapMap
View on HapMap

Homologs in model organisms

Mus musculus
Mt2
Rattus norvegicus
Mt1m
Rattus norvegicus
Mt2A

In other databases

GenAge microarray genes
  • This gene is present as MT1A
GenDR gene expression
  • A homolog of this gene for Mus musculus is present as Mt2

References

Cipriano et al. (2006)

Other variants which are also part of this study