LongevityMap variant
- Longevity Association
- Non-significant
- Population
- Italian
- Study Design
- The (T/C, 97347 bp) polymorphism was examined in healthy people 17-85 yr of age (n= 278; mean age, 54.8; 76 males and 202 females) and in healthy people 86-109 yr of age (n= 218; mean age, 98.0; 56 males and 162 females)
- Conclusions
- No significant differences relative to longevity were found
- HGNC symbol
- FOXO1
- Aliases
- FKH1; FKHR; FOXO1A
- Common name
- forkhead box O1
- Description
- This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. [provided by RefSeq, Jul 2008]
- Other longevity studies of this gene
- 30
- OMIM
- 136533
- Ensembl
- ENSG00000150907
- UniProt/Swiss-Prot
- FOXO1_HUMAN
- Entrez Gene
- 2308
- UniGene
- 370666
- HapMap
- View on HapMap
Homologs in model organisms
- Caenorhabditis elegans
- daf-16
- Danio rerio
- foxo1a
- Danio rerio
- foxo1b
- Drosophila melanogaster
- foxo
- Mus musculus
- Foxo1
- Rattus norvegicus
- Foxo1
- Saccharomyces cerevisiae
- HCM1
- GenAge model organism genes
- A homolog of this gene for Caenorhabditis elegans is present as daf-16
- A homolog of this gene for Drosophila melanogaster is present as foxo
- A homolog of this gene for Saccharomyces cerevisiae is present as HCM1
- GenAge human genes
- This gene is present as FOXO1
- GenDR gene manipulations
- A homolog of this gene for Drosophila melanogaster is present as foxo
- A homolog of this gene for Caenorhabditis elegans is present as daf-16
- CellAge
- This gene is present as FOXO1
Bonafè et al. (2003)
Other variants which are also part of this study
