Genes Commonly Altered During Ageing

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Entrez Gene ID HGNC symbol Common name Over/Underexpressed Other databases
19 ABCA1 ATP binding cassette subfamily A member 1 Overexpressed
125 ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide Overexpressed
132 ADK adenosine kinase Underexpressed
133 ADM adrenomedullin Overexpressed
182 JAG1 jagged canonical Notch ligand 1 Overexpressed
187 APLNR apelin receptor Underexpressed
199 AIF1 allograft inflammatory factor 1 Overexpressed
217 ALDH2 aldehyde dehydrogenase 2 family member Overexpressed
241 ALOX5AP arachidonate 5-lipoxygenase activating protein Overexpressed
272 AMPD3 adenosine monophosphate deaminase 3 Overexpressed
292 SLC25A5 solute carrier family 25 member 5 Underexpressed
301 ANXA1 annexin A1 Overexpressed
302 ANXA2 annexin A2 Overexpressed
306 ANXA3 annexin A3 Overexpressed
307 ANXA4 annexin A4 Overexpressed
308 ANXA5 annexin A5 Overexpressed
310 ANXA7 annexin A7 Overexpressed
316 AOX1 aldehyde oxidase 1 Overexpressed
347 APOD apolipoprotein D Overexpressed
348 APOE apolipoprotein E Overexpressed

Note: This dataset represents transcriptional signatures of mammalian ageing identifying based on our ageing microarray/RNA-seq meta-analysis.