- Symbol
- HIR1
- Name
- HIstone Regulation
- Organism
- Saccharomyces cerevisiae (AnAge)
- Observations
- Mean replicative lifespan decreased in the alpha and a strain
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Deletion
- Longevity Category
- Necessary for fitness
- Primary reference
-
- Observations
- Inactivation of any component of the Hir complex extended the median replicative life span by 25%-35%.
- % change in avg or median lifespan
- Replicative lifespan is 25-35% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Deletion
- Longevity Category
- Anti-Longevity
- Primary reference
-
- CellAge
- A homolog of this gene for Homo sapiens is present as HIRA
- Caenorhabditis elegans
- K10D2.1
- Danio rerio
- hira
- Drosophila melanogaster
- Hira
- Homo sapiens
- HIRA
- Mus musculus
- Hira
- Rattus norvegicus
- Hira
- Rattus norvegicus
- LOC100911837
- Rattus norvegicus
- Hira
- Rattus norvegicus
- LOC100911837
- Schizosaccharomyces pombe
- hip1
- Saccharomyces Genome Database
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (852275)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for HIR1 (Saccharomyces cerevisiae)