Caenorhabditis elegansGenAge entry for shc-1 (Caenorhabditis elegans)

Gene information (ID: 980)

Symbol
shc-1
Name
Src Homology domain C-terminal, adaptor homolog
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
shc-1(ok198) mutants display a strongly reduced mean adult life span (38% compared with wild type).
% change in avg or median lifespan
Average lifespan is 38% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Mutation
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Mus musculus is present as Shc1
    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as SHC1
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as SHC1
    CellAge gene expression
    • A homolog of this gene for Homo sapiens is present as SHC4

    Homologs in other organisms

    Danio rerio
    shc1
    Danio rerio
    SHC3
    Danio rerio
    shc2
    Drosophila melanogaster
    Shc
    Homo sapiens
    SHC4
    Homo sapiens
    SHC1
    Homo sapiens
    SHC3
    Homo sapiens
    SHC2
    Mus musculus
    Shc1
    Mus musculus
    Shc3
    Mus musculus
    Shc4
    Mus musculus
    Shc2
    Rattus norvegicus
    Shc3
    Rattus norvegicus
    Shc1
    Rattus norvegicus
    Shc2
    Rattus norvegicus
    Shc4

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (3565745)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar