GenAge entry for Ilp2 (Drosophila melanogaster)
Gene information (ID: 855)
- Symbol
- Ilp2
- Aliases
- CG8167; dilp; Dilp; DILP; Dilp; 2; dilp-2; dILP-2; Dilp-2;
- Name
- Insulin-related peptide
- Organism
- Drosophila melanogaster (AnAge)
Potential relevance to longevity and/or ageing
- Observations
- The ablated flies exhibited a significant increase in median and maximum lifespan over that of control flies and an increased resistance to oxidative stress and starvation.The mutants also exhibit increased storage of lipid and carbohydrate, reduced fecundity, and reduced tolerance of heat and cold.
- % change in max lifespan
- Maximum female lifespan is up to 40% higher; Maximum male lifespan is approximately 27% higher.
- % change in avg or median lifespan
- Median female lifespan is up to 33.5% higher; Median male lifespan is 10.5% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Deletion
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Observations
- RNA interference resulted in a 24% to 47% increase in median lifespan compared to controls.
- % change in avg or median lifespan
- Lifespan is 24-47% higher
- Lifespan Effect
- Increase
- Genetic Manipulation
- RNA interference
- Longevity Category
- Anti-Longevity
- Primary reference
-
In other databases
- GenDR gene manipulations
- This gene is present as Ilp2
Homologs in other organisms
No homologs found
External links
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (39150)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar