Mus musculusGenAge entry for Trp53bp1 (Mus musculus)

Gene information (ID: 830)

Symbol
Trp53bp1
Aliases
53BP1; m53BP1; Tp53bp1
Name
Transformation related protein 53 binding protein 1
Organism
Mus musculus (AnAge)

Potential relevance to longevity and/or ageing

Observations
An extended lifespan and near-wild-type longevity of 53BP1-/- mice in the BRCA1 mutation background was observed. This was also accompanied by a relative absence of various progeriod phenotypes.
Lifespan Effect
Increase
Genetic Manipulation
Deletion in the BRCA1 mutant background
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as TP53BP1
    CellAge
    • A homolog of this gene for Homo sapiens is present as TP53BP1

    Homologs in other organisms

    Caenorhabditis elegans
    hsr-9
    Danio rerio
    tp53bp1
    Homo sapiens
    TP53BP1
    Rattus norvegicus
    Tp53bp1

    External links

    Mouse Genome Informatics
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (27223)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar