GenAge entry for Trp53bp1 (Mus musculus)
Gene information (ID: 830)
- Symbol
- Trp53bp1
- Aliases
- 53BP1; m53BP1; Tp53bp1
- Name
- Transformation related protein 53 binding protein 1
- Organism
- Mus musculus (AnAge)
Potential relevance to longevity and/or ageing
- Observations
- An extended lifespan and near-wild-type longevity of 53BP1-/- mice in the BRCA1 mutation background was observed. This was also accompanied by a relative absence of various progeriod phenotypes.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Deletion in the BRCA1 mutant background
- Longevity Category
- Anti-Longevity
- Primary reference
-
In other databases
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as TP53BP1
- CellAge
- A homolog of this gene for Homo sapiens is present as TP53BP1
Homologs in other organisms
External links
- Mouse Genome Informatics
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (27223)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar