Saccharomyces cerevisiaeGenAge entry for YKU70 (Saccharomyces cerevisiae)

Gene information (ID: 776)

Symbol
YKU70
Aliases
HDF1; NES24
Name
Subunit of the telomeric Ku complex (Yku70p-Yku80p)
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Mutants had a shorter lifespan.
Lifespan Effect
Decrease
Genetic Manipulation
Mutation
Longevity Category
Necessary for fitness
Primary reference
    Observations
    Mean replicative lifespan decreased in the alpha and a strain
    Lifespan Effect
    Decrease
    Genetic Manipulation
    Deletion
    Longevity Category
    Necessary for fitness
    Primary reference

      In other databases

      GenAge model organism genes
      • A homolog of this gene for Caenorhabditis elegans is present as cku-70
      • A homolog of this gene for Mus musculus is present as Xrcc6
      GenAge human genes
      • A homolog of this gene for Homo sapiens is present as XRCC6
      LongevityMap
      • A homolog of this gene for Homo sapiens is present as XRCC6

      Homologs in other organisms

      Caenorhabditis elegans
      cku-70
      Danio rerio
      xrcc6
      Drosophila melanogaster
      Irbp
      Homo sapiens
      XRCC6
      Mus musculus
      Xrcc6
      Rattus norvegicus
      Xrcc6
      Schizosaccharomyces pombe
      pku70

      External links

      Saccharomyces Genome Database
      Search
      Ensembl
      Search
      Entrez Gene
      View on Entrez Gene database (855328)
      Homologues
      Search HomoloGene
      UniProt
      Search
      Internet
      Search Google or Search Google Scholar