- Symbol
- pnc-1
- Name
- Pyrazinamidase and NiCotinamidase
- Organism
- Caenorhabditis elegans (AnAge)
- Known functions and activities
- Nicotinamidase
- Observations
- Knockouts showed a 30% decrease in maximum lifespan. Overexpression of pnc-1 increased adult survival under oxidative stress but did not extend the lifespan.
- % change in max lifespan
- Maximum lifespan is 30% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Knockout
- Longevity Category
- Pro-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Drosophila melanogaster is present as Naam
- A homolog of this gene for Saccharomyces cerevisiae is present as PNC1
- GenDR gene manipulations
- This gene is present as pnc-1
- A homolog of this gene for Saccharomyces cerevisiae is present as PNC1
- Drosophila melanogaster
- Naam
- Saccharomyces cerevisiae
- PNC1
- Schizosaccharomyces pombe
- pnc1
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (176833)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar