GenAge entry for pnc-1 (Caenorhabditis elegans)
Gene information (ID: 741)
- Symbol
- pnc-1
- Name
- Pyrazinamidase and NiCotinamidase
- Organism
- Caenorhabditis elegans (AnAge)
- Known functions and activities
- Nicotinamidase
Potential relevance to longevity and/or ageing
- Observations
- Knockouts showed a 30% decrease in maximum lifespan. Overexpression of pnc-1 increased adult survival under oxidative stress but did not extend the lifespan.
- % change in max lifespan
- Maximum lifespan is 30% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Knockout
- Longevity Category
- Pro-Longevity
- Primary reference
-
In other databases
- GenAge model organism genes
- GenDR gene manipulations
Homologs in other organisms
External links
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (176833)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar