Caenorhabditis elegansGenAge entry for him-6 (Caenorhabditis elegans)

Gene information (ID: 640)

Symbol
him-6
Name
High Incidence of Males (increased X chromosome loss)
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Helicase involved in DNA repair and DNA condensation

Potential relevance to longevity and/or ageing

Observations
Mutants have a low brood size, a shortened lifespan, and an increased amount of germ-line apoptosis.
Lifespan Effect
Decrease
Genetic Manipulation
Mutation
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as SGS1
    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as BLM
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as BLM
    CellAge gene expression
    • A homolog of this gene for Homo sapiens is present as BLM

    Homologs in other organisms

    Danio rerio
    blm
    Drosophila melanogaster
    Blm
    Homo sapiens
    BLM
    Mus musculus
    Blm
    Rattus norvegicus
    Blm
    Saccharomyces cerevisiae
    SGS1
    Schizosaccharomyces pombe
    rqh1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (178201)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar