- Symbol
- Adcy5
- Aliases
- Ac5; AW121902
- Name
- adenylate cyclase 5
- Organism
- Mus musculus (AnAge)
- Known functions and activities
- Synthesis of cAMP
- Observations
- Knock out mice are resistant to cardiac stress, have an increased median lifespan of 30% and an increased maximal lifespan of 12%. They are also protected from age-related reduced bone density and susceptibility to fractures, and reduced cardiac function.
- % change in max lifespan
- Maximum lifespan is 12% higher.
- % change in avg or median lifespan
- Median lifespan is 30% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Knockout
- Longevity Category
- Anti-Longevity
- Primary reference
-
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as ADCY5
- GenDR gene manipulations
- This gene is present as Adcy5
- LongevityMap
- A homolog of this gene for Homo sapiens is present as ADCY5
- Danio rerio
- adcy5
- Drosophila melanogaster
- CG43373
- Homo sapiens
- ADCY5
- Rattus norvegicus
- Adcy5
- Mouse Genome Informatics
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (224129)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for Adcy5 (Mus musculus)