- Symbol
- ROM2
- Name
- GDP/GTP exchange protein (GEP) for Rho1p and Rho2p
- Organism
- Saccharomyces cerevisiae (AnAge)
- Known functions and activities
- Activator of protein kinase C
- Observations
- Deletion increased mean replicative lifespan by about 30%.
- % change in avg or median lifespan
- Average replicative lifespan is about 30% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Deletion
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Observations
- Replicative lifespan increased by 50% in the alpha strain and 20% in a strain
- % change in avg or median lifespan
- Replicative lifespan is 20-50% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Deletion
- Longevity Category
- Anti-Longevity
- Primary reference
-
- CellAge gene expression
- A homolog of this gene for Homo sapiens is present as ARHGEF3
- Caenorhabditis elegans
- Y105E8A.25
- Caenorhabditis elegans
- rhgf-1
- Danio rerio
- arhgef2
- Danio rerio
- arhgef28
- Danio rerio
- arhgef18b
- Danio rerio
- ARHGEF12 (1 of many)
- Danio rerio
- arhgef3
- Danio rerio
- arhgef11
- Danio rerio
- arhgef1b
- Danio rerio
- si:dkey-91i10.2
- Danio rerio
- arhgef1a
- Danio rerio
- AKAP13 (1 of many)
- Danio rerio
- arhgef18a
- Danio rerio
- net1
- Danio rerio
- arhgef3l
- Danio rerio
- si:ch211-272b8.6
- Danio rerio
- arhgef12b
- Danio rerio
- AKAP13 (1 of many)
- Drosophila melanogaster
- RhoGEF2
- Drosophila melanogaster
- CG10188
- Drosophila melanogaster
- RhoGEF64C
- Homo sapiens
- ARHGEF1
- Homo sapiens
- NET1
- Homo sapiens
- ARHGEF2
- Homo sapiens
- AKAP13
- Homo sapiens
- ARHGEF11
- Homo sapiens
- 0
- Homo sapiens
- ARHGEF3
- Homo sapiens
- ARHGEF18
- Homo sapiens
- ARHGEF12
- Homo sapiens
- ARHGEF28
- Homo sapiens
- ARHGEF1
- Mus musculus
- Arhgef11
- Mus musculus
- Arhgef3
- Mus musculus
- Akap13
- Mus musculus
- Arhgef12
- Mus musculus
- Net1
- Mus musculus
- Arhgef2
- Mus musculus
- Arhgef1
- Mus musculus
- Arhgef28
- Mus musculus
- Arhgef18
- Rattus norvegicus
- Net1
- Rattus norvegicus
- Arhgef1
- Rattus norvegicus
- Arhgef2
- Rattus norvegicus
- Arhgef18
- Rattus norvegicus
- Akap13
- Rattus norvegicus
- Arhgef11
- Rattus norvegicus
- Arhgef12
- Rattus norvegicus
- Arhgef3
- Rattus norvegicus
- Arhgef28
- Saccharomyces Genome Database
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (851086)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar