Saccharomyces cerevisiaeGenAge entry for GLN3 (Saccharomyces cerevisiae)

Gene information (ID: 307)

Symbol
GLN3
Name
Gln3p
Organism
Saccharomyces cerevisiae (AnAge)
Known functions and activities
Transcriptional activator of genes regulated by nitrogen catabolite repression

Potential relevance to longevity and/or ageing

Observations
Deletion extends chronological lifespan.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Replicative lifespan decreased by 20% in the alpha strain
    % change in avg or median lifespan
    Replicative lifespan is 20% lower.
    Lifespan Effect
    Decrease
    Genetic Manipulation
    Deletion
    Longevity Category
    Necessary for fitness
    Primary reference
      Observations
      Mean chronological lifespan strongly increased in the a strain
      Lifespan Effect
      Increase
      Genetic Manipulation
      Deletion
      Longevity Category
      Anti-Longevity
      Primary reference

        In other databases

        GenAge model organism genes
        • A homolog of this gene for Caenorhabditis elegans is present as elt-6
        • A homolog of this gene for Caenorhabditis elegans is present as egl-18
        LongevityMap
        • A homolog of this gene for Homo sapiens is present as GATA4
        CellAge
        • A homolog of this gene for Homo sapiens is present as GATA4

        Homologs in other organisms

        Caenorhabditis elegans
        elt-4
        Caenorhabditis elegans
        elt-6
        Caenorhabditis elegans
        egl-18
        Caenorhabditis elegans
        elt-2
        Caenorhabditis elegans
        elt-1
        Danio rerio
        gata2b
        Danio rerio
        gata1b
        Danio rerio
        trps1
        Danio rerio
        gata5
        Danio rerio
        gata6
        Danio rerio
        gata1a
        Danio rerio
        gata3
        Danio rerio
        gata2a
        Danio rerio
        gata4
        Drosophila melanogaster
        GATAe
        Drosophila melanogaster
        pnr
        Drosophila melanogaster
        srp
        Drosophila melanogaster
        grn
        Drosophila melanogaster
        GATAd
        Homo sapiens
        GATA6
        Homo sapiens
        TRPS1
        Homo sapiens
        GATA5
        Homo sapiens
        GATA4
        Homo sapiens
        GATA1
        Homo sapiens
        GATA2
        Homo sapiens
        GATA3
        Mus musculus
        Gata1
        Mus musculus
        Gata3
        Mus musculus
        Gata6
        Mus musculus
        Trps1
        Mus musculus
        Gata5
        Mus musculus
        Gata2
        Mus musculus
        Gata4
        Rattus norvegicus
        LOC108348091
        Rattus norvegicus
        Gata4
        Rattus norvegicus
        Gata1
        Rattus norvegicus
        Gata2
        Rattus norvegicus
        Gata6
        Rattus norvegicus
        Gata3
        Rattus norvegicus
        Trps1
        Rattus norvegicus
        Gata5

        External links

        Saccharomyces Genome Database
        Search
        Ensembl
        Search
        Entrez Gene
        View on Entrez Gene database (856763)
        Homologues
        Search HomoloGene
        UniProt
        Search
        Internet
        Search Google or Search Google Scholar