Saccharomyces cerevisiaeGenAge entry for TSA1 (Saccharomyces cerevisiae)

Gene information (ID: 2109)

Symbol
TSA1
Name
thioredoxin peroxidase TSA1
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Overexpression of Tsa1 in yeast extended lifespan in a Hsp70 chaperone-dependent and CR-independent manner and also counteracted the typical progressive fitness decline of ageing mother cells.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as prdx-2
    • A homolog of this gene for Caenorhabditis elegans is present as prdx-3
    • A homolog of this gene for Mus musculus is present as Prdx1
    • A homolog of this gene for Drosophila melanogaster is present as Jafrac1
    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as PRDX1
    GenDR gene manipulations
    • This gene is present as TSA1
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as PRDX3

    Homologs in other organisms

    Caenorhabditis elegans
    prdx-2
    Caenorhabditis elegans
    prdx-3
    Danio rerio
    prdx1
    Danio rerio
    prdx3
    Danio rerio
    prdx4
    Danio rerio
    prdx2
    Drosophila melanogaster
    Jafrac2
    Drosophila melanogaster
    Jafrac1
    Drosophila melanogaster
    CG6888
    Drosophila melanogaster
    Prx3
    Homo sapiens
    PRDX3
    Homo sapiens
    PRDX2
    Homo sapiens
    PRDX4
    Homo sapiens
    PRDX1
    Mus musculus
    Prdx3
    Mus musculus
    Prdx1
    Mus musculus
    Gm5225
    Mus musculus
    Prdx4
    Mus musculus
    Prdx2
    Rattus norvegicus
    Prdx4
    Rattus norvegicus
    AABR07012795.1
    Rattus norvegicus
    Prdx3
    Rattus norvegicus
    Prdx2
    Rattus norvegicus
    Prdx1

    External links

    Saccharomyces Genome Database
    Search
    Ensembl
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    Entrez Gene
    View on Entrez Gene database (854980)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar