- Symbol
- MET17
- Aliases
- MET15; MET25
- Name
- bifunctional cysteine synthase/O-acetylhomoserine aminocarboxypropyltransferase MET17
- Organism
- Saccharomyces cerevisiae (AnAge)
- Observations
- Knockout of MET17 (previously known as MET15), which causes only in a moderate defect in methionine biosynthesis, results in both longer maximum and median chronological lifespan. The experiment was performed in synthetic complete medium supplemented with 30 mg/l methionine, and the MET15 strain showed equivalent cell counts and comparable cell cycle arrest with the controls and met2 strain.
- % change in max lifespan
- Maximum chronological lifespan is approximately 115% higher.
- % change in avg or median lifespan
- Median chronological lifespan is more than 100% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Deletion
- Longevity Category
- Anti-Longevity
- Primary reference
-
- GenDR gene manipulations
- This gene is present as MET17
- Schizosaccharomyces pombe
- SPBC428.11
- Saccharomyces Genome Database
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (851010)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar