- Symbol
- ALG12
- Aliases
- ECM39
- Name
- Asparagine-Linked Glycosylation
- Organism
- Saccharomyces cerevisiae (AnAge)
- Observations
- Deletion of alg12, a target of the unfolded protein response signaling, increases replicative lifespan. This increase is dependant on Ire1p, a functional ER stress sensor protein.
- % change in avg or median lifespan
- Mean lifespan is 16% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Deletion
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Observations
- Replicative lifespan increased by 25% in both the alpha strain and the a strain
- % change in avg or median lifespan
- Replicative lifespan is 25% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Deletion
- Longevity Category
- Anti-Longevity
- Primary reference
-
- GenDR gene manipulations
- This gene is present as ALG12
- Caenorhabditis elegans
- ZC513.5
- Danio rerio
- alg12
- Drosophila melanogaster
- CG8412
- Homo sapiens
- ALG12
- Mus musculus
- Alg12
- Rattus norvegicus
- Alg12
- Schizosaccharomyces pombe
- alg12
- Saccharomyces Genome Database
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (855764)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for ALG12 (Saccharomyces cerevisiae)