Saccharomyces cerevisiaeGenAge entry for NPL3 (Saccharomyces cerevisiae)

Gene information (ID: 1372)

Symbol
NPL3
Aliases
MTR13; MTS1; NAB1; NOP3
Name
Nuclear Protein Localization
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Replicative lifespan decreased by 50% in the alpha strain
% change in avg or median lifespan
Replicative lifespan is 50% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Deletion
Longevity Category
Necessary for fitness
Primary reference
    Observations
    Mean chronological lifespan decreased in the a strain by less than 50% but more than 15%
    % change in avg or median lifespan
    Mean chronological lifespan is 15%-50% lower.
    Lifespan Effect
    Decrease
    Genetic Manipulation
    Deletion
    Longevity Category
    Necessary for fitness
    Primary reference

      In other databases

      GenAge microarray genes
      • A homolog of this gene for Homo sapiens is present as SRSF5
      CellAge
      • A homolog of this gene for Homo sapiens is present as SRSF1
      • A homolog of this gene for Homo sapiens is present as SRSF3
      CellAge gene expression
      • A homolog of this gene for Homo sapiens is present as SRSF3
      • A homolog of this gene for Homo sapiens is present as SRSF7

      Homologs in other organisms

      Caenorhabditis elegans
      rsp-2
      Caenorhabditis elegans
      rsp-3
      Caenorhabditis elegans
      rsp-6
      Caenorhabditis elegans
      Y57G11A.5
      Caenorhabditis elegans
      rsp-5
      Caenorhabditis elegans
      rsp-1
      Danio rerio
      srsf9
      Danio rerio
      srsf1a
      Danio rerio
      srsf6a
      Danio rerio
      srsf7a
      Danio rerio
      srsf3a
      Danio rerio
      srsf4
      Danio rerio
      srsf5a
      Danio rerio
      srsf3a
      Danio rerio
      srsf1b
      Danio rerio
      srsf5b
      Danio rerio
      srsf6b
      Danio rerio
      srsf3b
      Danio rerio
      srsf7b
      Drosophila melanogaster
      B52
      Drosophila melanogaster
      Rbp1-like
      Drosophila melanogaster
      SF2
      Drosophila melanogaster
      Rbp1
      Drosophila melanogaster
      Rsf1
      Drosophila melanogaster
      x16
      Homo sapiens
      SRSF7
      Homo sapiens
      SRSF9
      Homo sapiens
      SRSF4
      Homo sapiens
      SRSF5
      Homo sapiens
      SRSF3
      Homo sapiens
      SRSF1
      Homo sapiens
      SRSF6
      Mus musculus
      Gm12355
      Mus musculus
      Srsf6
      Mus musculus
      Srsf9
      Mus musculus
      Srsf4
      Mus musculus
      Srsf5
      Mus musculus
      Srsf3
      Mus musculus
      Srsf1
      Mus musculus
      Srsf7
      Rattus norvegicus
      Srsf4
      Rattus norvegicus
      Srsf5
      Rattus norvegicus
      Srsf1
      Rattus norvegicus
      Srsf7
      Rattus norvegicus
      Srsf6
      Rattus norvegicus
      AABR07055789.1
      Rattus norvegicus
      Srsf9
      Rattus norvegicus
      Srsf3
      Schizosaccharomyces pombe
      srp2

      External links

      Saccharomyces Genome Database
      Search
      Ensembl
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      Entrez Gene
      View on Entrez Gene database (852042)
      Homologues
      Search HomoloGene
      UniProt
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      Internet
      Search Google or Search Google Scholar