Caenorhabditis elegansGenAge entry for elo-5 (Caenorhabditis elegans)

Gene information (ID: 219)

Symbol
elo-5
Name
fatty acid ELOngation
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Polyunsaturated fatty acid (PUFA) elongase

Potential relevance to longevity and/or ageing

Observations
RNA interference decreased median lifespan by 45% in wild type animals and 29% in daf-2 mutants.
% change in avg or median lifespan
Median lifespan is 45% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenDR gene manipulations
    • A homolog of this gene for Saccharomyces cerevisiae is present as SUR4

    Homologs in other organisms

    Saccharomyces cerevisiae
    ELO1
    Saccharomyces cerevisiae
    ELO3
    Saccharomyces cerevisiae
    ELO2
    Schizosaccharomyces pombe
    SPAC1639.01c

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (177320)
    Homologues
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    UniProt
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    Internet
    Search Google or Search Google Scholar