Caenorhabditis elegansGenAge entry for eif-3.K (Caenorhabditis elegans)

Gene information (ID: 2091)

Symbol
eif-3.K
Name
Eukaryotic translation initiation factor 3 subunit K
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
In C. elegans mutants lacking eif-3.K, a nonessential eIF3 subunit, demonstrated a 40% increase in lifespan and enhanced resistance to endoplasmic reticulum stress.
% change in avg or median lifespan
Median lifespan is 40% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    eif3k
    Drosophila melanogaster
    CG10306
    Homo sapiens
    EIF3K
    Mus musculus
    Eif3k
    Rattus norvegicus
    Eif3k

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (179779)
    Homologues
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    UniProt
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    Internet
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