GenAge entry for dot-1.1 (Caenorhabditis elegans)
Gene information (ID: 2233)
- Symbol
- dot-1.1
- Name
- DOT1 histone methyltransferase
- Organism
- Caenorhabditis elegans (AnAge)
Potential relevance to longevity and/or ageing
- Observations
- Downregulation of dot-1.1 in post-reproductive rrf-3 worms (9 days) increased mean lifespan by 15%.
- % change in avg or median lifespan
- Mean lifespan is 15% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- RNA interference
- Longevity Category
- Anti-Longevity
- Primary reference
-
In other databases
- GenAge model organism genes
- A homolog of this gene for Saccharomyces cerevisiae is present as DOT1
- CellAge
- A homolog of this gene for Homo sapiens is present as DOT1L
Homologs in other organisms
- Danio rerio
- dot1l
- Drosophila melanogaster
- gpp
- Homo sapiens
- DOT1L
- Mus musculus
- Dot1l
- Rattus norvegicus
- Dot1l
- Saccharomyces cerevisiae
- DOT1
External links
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (171797)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar