Caenorhabditis elegansGenAge entry for aakb-2 (Caenorhabditis elegans)

Gene information (ID: 752)

Symbol
aakb-2
Name
AMP-Activated Kinase Beta subunit
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Protein involved in Snf1 protein kinase complex assembly

Potential relevance to longevity and/or ageing

Observations
RNA interference resulted in decreased lifespan and earlier accumulation of lipofuscin.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as SIP2

    Homologs in other organisms

    Danio rerio
    prkab1a
    Danio rerio
    PRKAB2
    Danio rerio
    prkab1b
    Drosophila melanogaster
    alc
    Homo sapiens
    PRKAB2
    Homo sapiens
    PRKAB1
    Mus musculus
    Prkab1
    Mus musculus
    Prkab2
    Rattus norvegicus
    Prkab1
    Rattus norvegicus
    Prkab2
    Saccharomyces cerevisiae
    GAL83
    Saccharomyces cerevisiae
    SIP2

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (176552)
    Homologues
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    UniProt
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    Internet
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