Mus musculusGenAge entry for Ubd (Mus musculus)

Gene information (ID: 1958)

Symbol
Ubd
Name
ubiquitin D
Organism
Mus musculus (AnAge)

Potential relevance to longevity and/or ageing

Observations
FAT10 (Ubd) knockout mice are leaner, live longer (~20%) and display reduced age-associated biomarkers (delayed sarcopenia, denser and smoother fur, absence of tumors).
% change in max lifespan
Maximum lifespan is approximately 20% higher.
% change in avg or median lifespan
Mean lifespan is approximately 20% higher.
Lifespan Effect
Increase
Genetic Manipulation
Knockout
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as UBI4

    Homologs in other organisms

    Caenorhabditis elegans
    ubq-1
    Drosophila melanogaster
    CG11700
    Homo sapiens
    UBD
    Rattus norvegicus
    Ubd
    Saccharomyces cerevisiae
    UBI4

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (24108)
    Homologues
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    UniProt
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    Internet
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