- Symbol
- Bub3
- Aliases
- C78067; AU019800; AU021329; AU043350; AW146323
- Name
- budding uninhibited by benzimidazoles 3 homolog (S. cerevisiae)
- Organism
- Mus musculus (AnAge)
- Known functions and activities
- Kinase involved in the spindle checkpoint function
- Observations
- Haploinsufficiency of Bub3 and Rae1, but not haploinsufficiency of either gene by itself, reduces lifespan by 12% and appears to accelerate ageing.
- % change in avg or median lifespan
- Lifespan is 12% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Mutation
- Longevity Category
- Pro-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Caenorhabditis elegans is present as bub-3
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as BUB3
- CellAge gene expression
- A homolog of this gene for Homo sapiens is present as BUB3
- Caenorhabditis elegans
- bub-3
- Danio rerio
- bub3
- Drosophila melanogaster
- Bub3
- Homo sapiens
- BUB3
- Rattus norvegicus
- Bub3
- Saccharomyces cerevisiae
- GLE2
- Schizosaccharomyces pombe
- bub3
- Mouse Genome Informatics
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (12237)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for Bub3 (Mus musculus)