Saccharomyces cerevisiaeGenAge entry for BST1 (Saccharomyces cerevisiae)

Gene information (ID: 1869)

Symbol
BST1
Aliases
PER17
Name
Bst1p
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Deletion of bst1, a target of the unfolded protein response signaling, increases replicative lifespan. This increase is dependant on Ire1p, a functional ER stress sensor protein.
% change in avg or median lifespan
Mean lifespan is 25% higher.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Caenorhabditis elegans
    T19B10.8
    Danio rerio
    pgap1
    Drosophila melanogaster
    CG3160
    Homo sapiens
    PGAP1
    Mus musculus
    Pgap1
    Rattus norvegicus
    Pgap1
    Schizosaccharomyces pombe
    bst1

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (850519)
    Homologues
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    UniProt
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    Internet
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