- Symbol
- Cav1
- Aliases
- Cav; Cav-1
- Name
- caveolin, caveolae protein 1
- Organism
- Mus musculus (AnAge)
- Known functions and activities
- Component of caveolae membranes in nonmuscle cells
- Observations
- Knockout mice are viable and fertile but exhibit an approximately 50% reduction in lifespan probably due to a combination of pulmonary fibrosis, pulmonary hypertension, and cardiac hypertrophy.
- % change in avg or median lifespan
- Lifespan is 50% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Knockout
- Longevity Category
- Pro-Longevity
- Primary reference
-
- CellAge
- A homolog of this gene for Homo sapiens is present as CAV1
- Danio rerio
- cav1
- Homo sapiens
- CAV1
- Rattus norvegicus
- Cav1
- Mouse Genome Informatics
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (12389)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for Cav1 (Mus musculus)