DrugAge entry for Coenzyme Q10

Name
Coenzyme Q10 
Synonyms
303-98-0 • Coenzyme Q • Coenzyme Q 10 • Coenzyme Q(sub 10) • Coenzyme Q-10 • Coenzyme Q10 • coenzyme-Q10 • CoQ 10 • CoQ10 • Emitolon • Heartcin • Inokiten • Justquinon • Luvacor • Neuquinon • Neuquinone • Terekol • ubidecarenone • Ubidecarenonum [Latin] • Ubiquinone • Ubiquinone 10 • Ubiquinone 50 • Ubiquinone Q10 • ubiquinone-10 • Udekinon 
CAS Number
303-98-0 
IUPAC Name
2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaenyl]-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione 
PubChem CID
5281915 

Summary

Species No. Entries MAX(Avg/Med Lifespan Change %) MEAN(Avg/Med Lifespan Change %) MAX(Max Lifespan Change %) MEAN(Max Lifespan Change %)

Results

Compound/Formulation Species Sex Strain Dosage Avg/Med Lifespan Change (%) Avg/Med Lifespan Significance Max Lifespan Change (%) Reference

Lifespan Charts for Coenzyme Q10


References

Ishii, N et al. (2004) Coenzyme Q10 can prolong C. elegans lifespan by lowering oxidative stress. Mech. Ageing Dev. 125(1)41-46 PubMed
Yang, YY et al. (2009) The effect of different ubiquinones on lifespan in Caenorhabditis elegans. Mech. Ageing Dev. 130(6)370-376 PubMed
Kimmo Lönnrot (1998) The effects of lifelong ubiquinone Q10 supplementation on the Q9 and Q10 tissue concentrations and life span of male rats and mice Biochemistry and Molecular Biology International 44(4)727-37 PubMed
Lee, CK et al. (2004) The impact of alpha-lipoic acid, coenzyme Q10 and caloric restriction on life span and gene expression patterns in mice. Free radical biology & medicine 36(8)1043-57 PubMed

DGIdb Human Drug-Gene Interactions for Coenzyme Q10

Interaction Types Gene Symbol Common Name HGNC Id DGIdb Sources References

Stitch DB Human Drug-Protein Interactions for Coenzyme Q10

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id StringDB Id