GenDR Dietary Restriction Gene Manipulation: hif-1
Gene Information (Entrez Gene ID: 180359)
- Symbol
- hif-1
- Name
- HIF (hypoxia inducible factor) homolog 1
- Organism
- Caenorhabditis elegans (AnAge)
- Entrez Gene ID
- 180359
Potential relevance to dietary restriction and ageing
- Observations
-
One study found that hif-1 mutation does not suppress lifespan extension of bacterial dilution DR or eat-2 mutation [2434]. hif-1 deletion extends lifespan by 24% and inhibition of hif-1 by RNAi also extends adult lifespan. hif-1 mutation extends lifespan under ad lib, but does not further extend lifespan extension under modified solid DR [2571].
- References
-
In other databases
- GenAge model organism genes
- This gene is present as hif-1
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as HIF1A
- LongevityMap
- A homolog of this gene for Homo sapiens is present as HIF1A
- CellAge
- CellAge gene expression
- A homolog of this gene for Homo sapiens is present as EPAS1
Homologs
- Danio rerio
- hif1al2
- Danio rerio
- hif1al
- Danio rerio
- hif1ab
- Danio rerio
- epas1b
- Danio rerio
- hif1aa
- Danio rerio
- epas1a
- Drosophila melanogaster
- sima
- Homo sapiens
- HIF1A
- Homo sapiens
- HIF3A
- Homo sapiens
- EPAS1
- Mus musculus
- Hif3a
- Mus musculus
- Epas1
- Mus musculus
- Hif1a
- Rattus norvegicus
- Epas1
- Rattus norvegicus
- Hif1a
- Rattus norvegicus
- Hif3a
External links
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- ID 180359
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar