GenDR Dietary Restriction Gene Manipulation: GIT3
Gene Information (Entrez Gene ID: 2538770)
- G-protein coupled receptor Git3
- Schizosaccharomyces pombe (AnAge)
- Entrez Gene ID
Potential relevance to dietary restriction and ageing
GIT3 encodes a G protein-coupled receptor for glucose. Git3 deletion increases chronological lifespan in conditions where glucose consumption is not affected. Constitutive activation of Galpha subunit acting downstream of Git3 accelerates aging and inhibits effect of DR .
No homologs found