Saccharomyces cerevisiae GenDR Dietary Restriction Gene Manipulation: ERG5

Gene Information (Entrez Gene ID: 855029)

Symbol
ERG5
Aliases
CYP61
Name
ERGosterol biosynthesis 5
Organism
Saccharomyces cerevisiae (AnAge)
Entrez Gene ID
855029

Potential relevance to dietary restriction and ageing

Observations

Deletion of ERG5 decreases replicative lifespan by 35% in the a strain [2504], but increases mean chronological lifespan by 26 - 116% (26, 40, 43, 62, 116) in diploid cells [2593]. Deletion of ERG5 cancels out the replicative lifespan extension of 0.5% glucose restriction [2514].

References

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as cyp-33E2
    • A homolog of this gene for Caenorhabditis elegans is present as daf-9
    • This gene is present as ERG5

    Homologs

    Caenorhabditis elegans
    cyp-33C6
    Caenorhabditis elegans
    cyp-33E3
    Caenorhabditis elegans
    cyp-33E2
    Caenorhabditis elegans
    cyp-33C7
    Caenorhabditis elegans
    cyp-33E1
    Caenorhabditis elegans
    daf-9
    Caenorhabditis elegans
    cyp-36A1
    Caenorhabditis elegans
    cyp-33C1
    Caenorhabditis elegans
    cyp-33D1
    Caenorhabditis elegans
    cyp-14A1
    Caenorhabditis elegans
    cyp-33D3
    Caenorhabditis elegans
    cyp-33C11
    Caenorhabditis elegans
    cyp-33C3
    Caenorhabditis elegans
    cyp-33C12
    Caenorhabditis elegans
    cyp-33C8
    Caenorhabditis elegans
    cyp-14A2
    Caenorhabditis elegans
    cyp-14A3
    Caenorhabditis elegans
    cyp-14A4
    Caenorhabditis elegans
    cyp-33A1
    Caenorhabditis elegans
    cyp-33B1
    Caenorhabditis elegans
    cyp-23A1
    Caenorhabditis elegans
    cyp-14A5
    Caenorhabditis elegans
    cyp-33C4
    Caenorhabditis elegans
    cyp-33C2
    Caenorhabditis elegans
    cyp-33C5
    Caenorhabditis elegans
    cyp-33C9
    Danio rerio
    cyp21a2
    Danio rerio
    cyp17a2
    Danio rerio
    cyp17a1
    Drosophila melanogaster
    phm
    Drosophila melanogaster
    spok
    Drosophila melanogaster
    spo
    Drosophila melanogaster
    Cyp303a1
    Drosophila melanogaster
    Cyp304a1
    Drosophila melanogaster
    Cyp305a1
    Homo sapiens
    CYP17A1
    Homo sapiens
    CYP21A2
    Mus musculus
    Cyp2b23
    Mus musculus
    Cyp2a12
    Mus musculus
    Cyp21a1
    Mus musculus
    Cyp17a1
    Rattus norvegicus
    Cyp17a1
    Rattus norvegicus
    Cyp2a1
    Rattus norvegicus
    Cyp2a1
    Rattus norvegicus
    Cyp21a1
    Schizosaccharomyces pombe
    erg5

    External links

    Saccharomyces Genome Database
    Search
    Ensembl
    Search
    Entrez Gene
    ID 855029
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar