Caenorhabditis elegans GenDR Dietary Restriction Gene Manipulation: nsy-1

Gene Information (Entrez Gene ID: 24104671)

Symbol
nsy-1
Name
Neuronal SYmmetry
Organism
Caenorhabditis elegans (AnAge)
Entrez Gene ID
24104671

Potential relevance to dietary restriction and ageing

Observations

Loss-of-function nsy-1 mutant reduces the lifespan extension of intermitent fasting. In the wild-type N2 worms, intermitent fasting increases lifespan by ~77%, while in the nsy-1 mutants lifespan extension is reduced to ~50%.

References

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as BCK1
    • A homolog of this gene for Saccharomyces cerevisiae is present as STE11
    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as MAP3K5
    GenDR gene expression
    • A homolog of this gene for Mus musculus is present as Map3k6
    CellAge
    • A homolog of this gene for Homo sapiens is present as MAP3K6

    Homologs

    Danio rerio
    map3k5
    Danio rerio
    map3k15
    Danio rerio
    MAP3K6
    Drosophila melanogaster
    Pk92B
    Homo sapiens
    MAP3K6
    Homo sapiens
    MAP3K5
    Homo sapiens
    MAP3K15
    Mus musculus
    Map3k15
    Mus musculus
    Map3k5
    Mus musculus
    Map3k6
    Rattus norvegicus
    Map3k15
    Rattus norvegicus
    AABR07038021.1
    Rattus norvegicus
    Map3k6
    Rattus norvegicus
    Map3k5
    Saccharomyces cerevisiae
    STE11
    Saccharomyces cerevisiae
    BCK1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    ID 24104671
    Homologues
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    UniProt
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    Internet
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