GenDR Dietary Restriction Gene Manipulation: nsy-1
Gene Information (Entrez Gene ID: 24104671)
Potential relevance to dietary restriction and ageing
- Observations
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Loss-of-function nsy-1 mutant reduces the lifespan extension of intermitent fasting. In the wild-type N2 worms, intermitent fasting increases lifespan by ~77%, while in the nsy-1 mutants lifespan extension is reduced to ~50%.
- References
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In other databases
- GenAge model organism genes
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as MAP3K5
- GenDR gene expression
- A homolog of this gene for Mus musculus is present as Map3k6
- CellAge
Homologs
- Danio rerio
- map3k5
- Danio rerio
- map3k15
- Danio rerio
- MAP3K6
- Drosophila melanogaster
- Pk92B
- Homo sapiens
- MAP3K6
- Homo sapiens
- MAP3K5
- Homo sapiens
- MAP3K15
- Mus musculus
- Map3k15
- Mus musculus
- Map3k5
- Mus musculus
- Map3k6
- Rattus norvegicus
- Map3k15
- Rattus norvegicus
- AABR07038021.1
- Rattus norvegicus
- Map3k6
- Rattus norvegicus
- Map3k5
- Saccharomyces cerevisiae
- STE11
- Saccharomyces cerevisiae
- BCK1
External links
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- ID 24104671
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar