Saccharomyces cerevisiae GenDR Dietary Restriction Gene Manipulation: MSN4

Gene Information (Entrez Gene ID: 853803)

Symbol
MSN4
Name
Multicopy suppressor of SNF1 mutation 4
Organism
Saccharomyces cerevisiae (AnAge)
Entrez Gene ID
853803

Potential relevance to dietary restriction and ageing

Observations

Deletion of MSN2 and MSN4 extends replicative lifespan [2559]. Deletion of MSN2 and MSN4 does not significantly decrease chronological lifespan under ad libitum, but attenuates chronological lifespan extension by water starvation and 0.5% glucose restriction [2556]. msn2 msn4 has no effect on replicative lifespan in PSY316, and does not prevent lifespan extension by DR [2260].

References

    In other databases

    LongevityMap
    • A homolog of this gene for Homo sapiens is present as MECOM

    Homologs

    Caenorhabditis elegans
    egl-43
    Danio rerio
    mecom
    Danio rerio
    PRDM16
    Drosophila melanogaster
    ken
    Drosophila melanogaster
    CG10348
    Drosophila melanogaster
    ham
    Homo sapiens
    PRDM16
    Homo sapiens
    MECOM
    Mus musculus
    Mecom
    Mus musculus
    Prdm16
    Rattus norvegicus
    Prdm16
    Rattus norvegicus
    Mecom

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    ID 853803
    Homologues
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    UniProt
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    Internet
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