GenDR Dietary Restriction Gene Manipulation: TSA1
Gene Information (Entrez Gene ID: 854980)
- Symbol
- TSA1
- Aliases
- TPX1 ZRG14
- Name
- Thiol-Specific Antioxidant 1
- Organism
- Saccharomyces cerevisiae (AnAge)
- Entrez Gene ID
- 854980
Potential relevance to dietary restriction and ageing
- Observations
-
Disruption of TSA1 shortens chronological lifespan [2633]. Replicative lifespan extension by DR in sir2;fob1 double mutant is reduced by TSA1 deletion mutant. Wild-type cells require TSA1 to fully extend lifespan. Mutation in CDC35 (adenylate cyclase), a genetic mimetic of DR, is dependent on TSA1 to extend lifespan [2587].
- References
-
In other databases
- GenAge model organism genes
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as PRDX1
- GenAge microarray genes
- A homolog of this gene for Homo sapiens is present as PRDX3
- LongevityMap
- A homolog of this gene for Homo sapiens is present as PRDX3
Homologs
- Caenorhabditis elegans
- prdx-2
- Caenorhabditis elegans
- prdx-3
- Danio rerio
- prdx1
- Danio rerio
- prdx3
- Danio rerio
- prdx4
- Danio rerio
- prdx2
- Drosophila melanogaster
- Jafrac2
- Drosophila melanogaster
- Jafrac1
- Drosophila melanogaster
- CG6888
- Drosophila melanogaster
- Prx3
- Homo sapiens
- PRDX3
- Homo sapiens
- PRDX2
- Homo sapiens
- PRDX4
- Homo sapiens
- PRDX1
- Mus musculus
- Prdx3
- Mus musculus
- Prdx1
- Mus musculus
- Gm5225
- Mus musculus
- Prdx4
- Mus musculus
- Prdx2
- Rattus norvegicus
- Prdx4
- Rattus norvegicus
- AABR07012795.1
- Rattus norvegicus
- Prdx3
- Rattus norvegicus
- Prdx2
- Rattus norvegicus
- Prdx1
External links
- Saccharomyces Genome Database
- Search
- Ensembl
- Search
- Entrez Gene
- ID 854980
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar