Drosophila melanogaster GenDR Dietary Restriction Gene Manipulation: ms(3)72Dt

Gene Information (Entrez Gene ID: 39761)

Symbol
ms(3)72Dt
Aliases
CG5389 Dmel\CG5389
Name
male sterile (3) 72Dt
Organism
Drosophila melanogaster (AnAge)
Entrez Gene ID
39761

Potential relevance to dietary restriction and ageing

Observations

RNAi of complex V subunit CG5389 (ms(3)72Dt) results in increased mean longevity under standard laboratory food conditions (3% yeast) in males [2389]. Under rich media conditions CG5389 knockdown throughout development and adulthood increases mean lifespan by 26% and abolished the lifespan extension by DR in males [2610].

References

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as ATP2
    • This gene is present as CG5389

    Homologs

    Saccharomyces cerevisiae
    ATP2

    External links

    FlyBase
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    Entrez Gene
    ID 39761
    Homologues
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