Caenorhabditis elegans GenDR Dietary Restriction Gene Manipulation: cbp-1

Gene Information (Entrez Gene ID: 176380)

Symbol
cbp-1
Name
CBP/p300 homolog 1
Organism
Caenorhabditis elegans (AnAge)
Entrez Gene ID
176380

Potential relevance to dietary restriction and ageing

Observations

Bacterial dilution DR induces cbp-1 expression. Overexpression of cbp-1 does not significantly affect lifespan. cbp-1 RNAi specifically in adults completely blocks lifespan extension by three distinct protocols of DR, partly by daf-2 mutation but not of cold and blocks the delay of other age-related pathologies by bacterial dilution DR [2569].

References

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as CREBBP
    • A homolog of this gene for Homo sapiens is present as EP300

    Homologs

    Danio rerio
    crebbpa
    Danio rerio
    crebbpb
    Danio rerio
    ep300b
    Danio rerio
    ep300a
    Drosophila melanogaster
    nej
    Homo sapiens
    CREBBP
    Homo sapiens
    EP300
    Mus musculus
    Ep300
    Mus musculus
    Crebbp
    Rattus norvegicus
    Crebbp
    Rattus norvegicus
    Ep300
    Saccharomyces cerevisiae
    BDF2
    Saccharomyces cerevisiae
    BDF1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    ID 176380
    Homologues
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    UniProt
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    Internet
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