Drosophila melanogaster GenDR Dietary Restriction Gene Manipulation: Ilp5

Gene Information (Entrez Gene ID: 2768992)

Symbol
Ilp5
Aliases
CG33273 dilp Dilp DILP Dilp 5 dilp-5 dILP-5 Dilp-5 dilp5 dIlp5 dILP5 Dilp5 DILP5 Dmel\CG33273 Ilp Ilp-5 ilp5 ILP5
Name
Insulin-like peptide 5
Organism
Drosophila melanogaster (AnAge)
Entrez Gene ID
2768992

Potential relevance to dietary restriction and ageing

Observations

Abundance of Ilp5 mRNA is reduced under DR. Ilp5 null mutants have a normal lifespan under ad libitum and a normal DR response. Ilp2 Ilp3 Ilp5 triple null mutants fail to have a normal response to DR. Their response is right shifted, with mutants being shorter-lived compared to wild-type on low but longer-lived on high yeast concentrations [2580].

References

    Homologs

    No homologs found

    External links

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    Entrez Gene
    ID 2768992
    Homologues
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