Saccharomyces cerevisiae GenDR Dietary Restriction Gene Manipulation: GIS1

Gene Information (Entrez Gene ID: 851670)

Symbol
GIS1
Name
GIg1-2 Suppressor 1
Organism
Saccharomyces cerevisiae (AnAge)
Entrez Gene ID
851670

Potential relevance to dietary restriction and ageing

Observations

Deletion of GIS1 increases replicative lifespan by 25% in the alpha strain [2503]and causes a major, although not complete, reversion of chronological lifespan extension by 0.5% glucose restriction [2556].

References

    In other databases

    GenAge model organism genes
    • This gene is present as GIS1
    • A homolog of this gene for Caenorhabditis elegans is present as jmjd-2
    CellAge
    • A homolog of this gene for Homo sapiens is present as KDM4A

    Homologs

    Caenorhabditis elegans
    jmjd-2
    Danio rerio
    kdm4ab
    Danio rerio
    kdm4aa
    Danio rerio
    kdm4c
    Danio rerio
    kdm4b
    Drosophila melanogaster
    Kdm4B
    Drosophila melanogaster
    Kdm4A
    Homo sapiens
    KDM4F
    Homo sapiens
    KDM4E
    Homo sapiens
    KDM4A
    Homo sapiens
    KDM4C
    Homo sapiens
    KDM4D
    Homo sapiens
    KDM4B
    Mus musculus
    Kdm4a
    Mus musculus
    Kdm4c
    Mus musculus
    Kdm4b
    Mus musculus
    Kdm4d
    Rattus norvegicus
    LOC108348070
    Rattus norvegicus
    Kdm4d
    Rattus norvegicus
    Kdm4c
    Rattus norvegicus
    Kdm4b
    Rattus norvegicus
    Kdm4a
    Rattus norvegicus
    LOC108348070

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    ID 851670
    Homologues
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    UniProt
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    Internet
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