Saccharomyces cerevisiae GenDR Dietary Restriction Gene Manipulation: FKH1

Gene Information (Entrez Gene ID: 854675)

Symbol
FKH1
Name
ForK head Homolog 1
Organism
Saccharomyces cerevisiae (AnAge)
Entrez Gene ID
854675

Potential relevance to dietary restriction and ageing

Observations

Deletion of FKH1 or FKH2 has no effect on neither replicative, nor chronological lifespan [2556]. Deletion of both FKH1 and FKH2 reduces mean chronological lifespan by 50% and abrogates lifespan extension and increased stress resistance conferred from water starvation (extreme DR). Modest increase in FKH1 or FKH2 expression results in a slight increased chronological and replicative lifespan as well as stress resistance [2614].

References

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as fkh-7

    Homologs

    Caenorhabditis elegans
    fkh-8
    Caenorhabditis elegans
    fkh-7
    Caenorhabditis elegans
    fkh-6
    Caenorhabditis elegans
    let-381
    Caenorhabditis elegans
    fkh-2
    Danio rerio
    foxj2
    Danio rerio
    foxp4
    Danio rerio
    foxp1a
    Danio rerio
    foxf1
    Danio rerio
    foxp3a
    Danio rerio
    foxp1b
    Danio rerio
    foxp2
    Danio rerio
    foxj1b
    Danio rerio
    foxk2
    Danio rerio
    foxh1
    Danio rerio
    foxk1
    Danio rerio
    foxq1b
    Danio rerio
    foxf2a
    Danio rerio
    foxg1b
    Danio rerio
    foxg1a
    Danio rerio
    foxg1c
    Danio rerio
    foxg1d
    Danio rerio
    foxj1a
    Danio rerio
    si:dkey-7e14.3
    Danio rerio
    foxf2b
    Danio rerio
    FOXK2 (1 of many)
    Danio rerio
    foxj3
    Danio rerio
    foxq1a
    Danio rerio
    foxp3b
    Drosophila melanogaster
    fd68A
    Drosophila melanogaster
    slp2
    Drosophila melanogaster
    FoxP
    Drosophila melanogaster
    slp1
    Drosophila melanogaster
    fd19B
    Drosophila melanogaster
    bin
    Homo sapiens
    FOXJ1
    Homo sapiens
    FOXK2
    Homo sapiens
    FOXK1
    Homo sapiens
    FOXH1
    Homo sapiens
    100288524
    Homo sapiens
    FOXF2
    Homo sapiens
    FOXP1
    Homo sapiens
    FOXJ2
    Homo sapiens
    FOXP3
    Homo sapiens
    FOXP2
    Homo sapiens
    FOXQ1
    Homo sapiens
    FOXF1
    Homo sapiens
    FOXP4
    Homo sapiens
    FOXJ3
    Homo sapiens
    FOXG1
    Mus musculus
    Foxj3
    Mus musculus
    Foxp3
    Mus musculus
    Foxk1
    Mus musculus
    Foxj2
    Mus musculus
    Foxk2
    Mus musculus
    Foxp4
    Mus musculus
    Foxg1
    Mus musculus
    Foxf1
    Mus musculus
    Foxh1
    Mus musculus
    Foxf2
    Mus musculus
    Foxq1
    Mus musculus
    Foxj1
    Mus musculus
    Foxp1
    Mus musculus
    Foxp2
    Mus musculus
    Gm5294
    Mus musculus
    Gm43517
    Rattus norvegicus
    Foxp4
    Rattus norvegicus
    Foxp2
    Rattus norvegicus
    Foxj2
    Rattus norvegicus
    Foxf1
    Rattus norvegicus
    Foxp3
    Rattus norvegicus
    Foxk2
    Rattus norvegicus
    Foxp1
    Rattus norvegicus
    Foxk1
    Rattus norvegicus
    Foxh1
    Rattus norvegicus
    Foxg1
    Rattus norvegicus
    LOC680273
    Rattus norvegicus
    Foxj3

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    ID 854675
    Homologues
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    UniProt
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    Internet
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