GenDR Dietary Restriction Gene Manipulation: AIM4
Gene Information (Entrez Gene ID: 852493)
- Altered Inheritance rate of Mi 4
- Saccharomyces cerevisiae (AnAge)
- Entrez Gene ID
Potential relevance to dietary restriction and ageing
AIM4 (alias SOY1) deletion increases chronological and replication lifespan, which is non-additive with DR. Under ad libitum mean and maximum replicative lifespan are extended by 63 and 69%, respectively. DR appears to decrease aim4-induced replication lifespan extension, indicating a negative interaction. aim4 mutation does not change DR-induced chronological lifespan extension .
No homologs found