LongevityMap Gene

Gene details

HGNC symbol
RRAGD 
Aliases
RAGD; bA11D8.2.1 
Common name
Ras related GTP binding D 
Description
RRAGD is a monomeric guanine nucleotide-binding protein, or G protein. By binding GTP or GDP, small G proteins act as molecular switches in numerous cell processes and signaling pathways.[supplied by OMIM, Apr 2004]
Cytogenetic Location
6q15
UCSC Genome Browser
View 6q15 on the UCSC genome browser
OMIM
608268
Ensembl
ENSG00000025039
UniProt/Swiss-Prot
RRAGD_HUMAN
Entrez Gene
58528
UniGene
31712
1000 Genomes
1000 Genomes

Homologs in model organisms

Danio rerio
rragd
Drosophila melanogaster
RagC
Mus musculus
Rragd
Rattus norvegicus
Rragd
Saccharomyces cerevisiae
GTR2
Schizosaccharomyces pombe
gtr2

Studies (1)

Significant/Non-significant: 1/0

Longevity Association
Significant
Population
Dutch
Study Design
1,018 SNPs within a 10-kb window around 40 mTOR signalling genes were studied for differences in variation between 417 unrelated nonagenarian participants and 476 younger controls
Conclusions
As a whole, there was a significant association of genetic variation in the mTOR pathway and familial longevity, though no individual gene was significant after correcting for multiple hypothesis testing
Indentifier
RRAGD
Reference