LongevityMap Gene
Gene details
- HGNC symbol
- RNR2
- Aliases
- MTRNR2
- Common name
- Description
- Cytogenetic Location
- MT
- UCSC Genome Browser
- View MT on the UCSC genome browser
- OMIM
- 561010
- Ensembl
- UniProt/Swiss-Prot
- Entrez Gene
- 4550
- UniGene
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
No homologs found
Studies (1)
Significant/Non-significant: 1/0
- Longevity Association
- Significant
- Population
- Japanese
- Study Design
- 11 Japanese centenarians and 43 controls were sequenced to identify the substitution differences between centenarians and controls. Then the identified variants were examined in 37 centenarians and 252 healthy controls.
- Conclusions
- All tested centenarians with both Mt8414T and Mt3010A carried Mt5178A. Mt5178A was related to longevity, and Mt5178C carriers were more susceptible to adult-onset diseases than those with Mt5178A.
- Indentifier
- Mt3010G/A
- Reference