LongevityMap Gene

Gene details

HGNC symbol
RNR2 
Aliases
MTRNR2 
Common name
 
Description
Cytogenetic Location
MT
UCSC Genome Browser
View MT on the UCSC genome browser
OMIM
561010
Ensembl
UniProt/Swiss-Prot
Entrez Gene
4550
UniGene
1000 Genomes
1000 Genomes

Homologs in model organisms

No homologs found

Studies (1)

Significant/Non-significant: 1/0

Longevity Association
Significant
Population
Japanese
Study Design
11 Japanese centenarians and 43 controls were sequenced to identify the substitution differences between centenarians and controls. Then the identified variants were examined in 37 centenarians and 252 healthy controls.
Conclusions
All tested centenarians with both Mt8414T and Mt3010A carried Mt5178A. Mt5178A was related to longevity, and Mt5178C carriers were more susceptible to adult-onset diseases than those with Mt5178A.
Indentifier
Mt3010G/A
Reference