LongevityMap Gene

Gene details

HGNC symbol
REM2 
Aliases
 
Common name
RRAD and GEM like GTPase 2 
Description
Cytogenetic Location
14q11.2
UCSC Genome Browser
View 14q11.2 on the UCSC genome browser
OMIM
616955
Ensembl
ENSG00000139890
UniProt/Swiss-Prot
REM2_HUMAN
Entrez Gene
161253
UniGene
444911
1000 Genomes
1000 Genomes

Homologs in model organisms

Mus musculus
Rem2
Rattus norvegicus
Rem2

Studies (1)

Significant/Non-significant: 0/1

Longevity Association
Non-significant
Population
Caucasians
Study Design
Meta-analysis of GWAS in Caucasians from four prospective cohort studies: the Age, Gene/Environment Susceptibility-Reykjavik Study, the Cardiovascular Health Study, the Framingham Heart Study, and the Rotterdam Study participating in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium. Longevity was defined as survival to age 90 years or older (n = 1,836); the comparison group comprised cohort members who died between the ages of 55 and 80 years (n = 1,955).
Conclusions
There were 273 single-nucleotide polymorphism (SNP) associations with p < .0001, but none reached significance after correcting for multiple testing
Indentifier
rs12891954
Reference