LongevityMap Gene

Gene details

HGNC symbol
MTA3 
Aliases
 
Common name
metastasis associated 1 family member 3 
Description
Cytogenetic Location
2p21
UCSC Genome Browser
View 2p21 on the UCSC genome browser
OMIM
609050
Ensembl
ENSG00000057935
UniProt/Swiss-Prot
D6W5A2_HUMAN
Entrez Gene
57504
UniGene
435413
1000 Genomes
1000 Genomes

Homologs in model organisms

Danio rerio
mta3
Mus musculus
Mta3
Rattus norvegicus
Mta3

Studies (1)

Significant/Non-significant: 0/1

Longevity Association
Non-significant
Population
Caucasians
Study Design
Meta-analysis of GWAS in Caucasians from four prospective cohort studies: the Age, Gene/Environment Susceptibility-Reykjavik Study, the Cardiovascular Health Study, the Framingham Heart Study, and the Rotterdam Study participating in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium. Longevity was defined as survival to age 90 years or older (n = 1,836); the comparison group comprised cohort members who died between the ages of 55 and 80 years (n = 1,955).
Conclusions
There were 273 single-nucleotide polymorphism (SNP) associations with p < .0001, but none reached significance after correcting for multiple testing
Indentifier
rs17029781
Reference