LongevityMap Gene

Gene details

HGNC symbol
LOC105376622 
Aliases
 
Common name
uncharacterized LOC105376622 
Description
Cytogenetic Location
11p13
UCSC Genome Browser
View 11p13 on the UCSC genome browser
OMIM
Ensembl
UniProt/Swiss-Prot
Entrez Gene
105376622
UniGene
1000 Genomes
1000 Genomes

Homologs in model organisms

No homologs found

Studies (1)

Significant/Non-significant: 0/1

Longevity Association
Non-significant
Population
Danish
Study Design
38 genes (311 SNPs) belonging to pro-antioxidant pathways were investigated for the association with physical and cognitive performances in a Cohort of 1089 Danish nonagenarians. For each gene analyzed in the pro-antioxidant pathway, the influence on longitudinal survival was tested.
Conclusions
No gene found associated with a functional phenotype showed a corresponding association with survival in the whole cohort. NDUFS1, TXNRD1, SOD2 and UCP3 were found significantly associated with lifespan in the female cohort. No association with survival was reported in males for genes belonging to the pro-oxidant pathway here analyzed.
Indentifier
rs208682
Reference