LongevityMap Gene

Gene details

HGNC symbol
LOC105375494 
Aliases
 
Common name
uncharacterized LOC105375494 
Description
Cytogenetic Location
7q32.1
UCSC Genome Browser
View 7q32.1 on the UCSC genome browser
OMIM
Ensembl
UniProt/Swiss-Prot
Entrez Gene
105375494
UniGene
1000 Genomes
1000 Genomes

Homologs in model organisms

No homologs found

Studies (1)

Significant/Non-significant: 1/0

Longevity Association
Significant
Population
Jordanian
Study Design
SNPs rs266729 (-11377G/C), rs2241766 (+45T/G), and rs1501299 (+276 G/T) of adiponectin gene (ADIPQO) and rs7799039 (-2548C/A) SNP of leptin (LEP) gene were genotyped in 110 randomly selected elderly subjects (>85 years old) with mean age of 90.2 years, and 120 young control subjects (range from 20 to 50 years) with mean age of 32.0 years
Conclusions
No significant differences were detected in the genotype and allele frequencies of examined gene variants between the two groups (p > 0.05). However, when gender was considered, genotypes and alleles frequencies of rs1501299 SNP in ADIPOQ gene and rs7799039 in LEP gene were significantly associated with longevity in men (p < 0.02) but not in women (p > 0.05).
Indentifier
rs7799039
Reference