LongevityMap Gene

Gene details

HGNC symbol
LMO4 
Aliases
 
Common name
LIM domain only 4 
Description
This gene encodes a cysteine-rich protein that contains two LIM domains but lacks a DNA-binding homeodomain. The encoded protein may play a role as a transcriptional regulator or as an oncogene. [provided by RefSeq, Aug 2008]
Cytogenetic Location
1p22.3
UCSC Genome Browser
View 1p22.3 on the UCSC genome browser
OMIM
603129
Ensembl
ENSG00000143013
UniProt/Swiss-Prot
LMO4_HUMAN
Entrez Gene
8543
UniGene
436792
1000 Genomes
1000 Genomes

Homologs in model organisms

Caenorhabditis elegans
CELE_Y1A5A.1
Danio rerio
lmo4b
Drosophila melanogaster
CG5708
Mus musculus
Lmo4
Rattus norvegicus
Lmo4

Studies (1)

Significant/Non-significant: 0/1

Longevity Association
Non-significant
Population
European
Study Design
Meta-analysis of genome-wide association studies of survival and survival free of major disease or death. In total, there were 25,007 participants over 55 years of age and followed-up for over 10 years for mortality and over 8 years for event-free survival.
Conclusions
No SNP was significantly associated with mortality after correcting for multiple testing, but 14 independent SNPs were associated with time to death at a suggestive threshold
Indentifier
rs11582903
Reference