LongevityMap Gene

Gene details

HGNC symbol
KIF26B 
Aliases
 
Common name
kinesin family member 26B 
Description
The protein encoded by this gene is an intracellular motor protein thought to transport organelles along microtubules. The encoded protein is required for kidney development. Elevated levels of this protein have been found in some breast and colorectal cancers. [provided by RefSeq, Mar 2017]
Cytogenetic Location
1q44
UCSC Genome Browser
View 1q44 on the UCSC genome browser
OMIM
614026
Ensembl
ENSG00000162849
UniProt/Swiss-Prot
B7WPD9_HUMAN
Entrez Gene
55083
UniGene
143134
1000 Genomes
1000 Genomes

Homologs in model organisms

Danio rerio
uncharacterized_E7FD
Mus musculus
Kif26b
Rattus norvegicus
Kif26b

Studies (1)

Significant/Non-significant: 0/1

Longevity Association
Non-significant
Population
German
Study Design
Genome-wide association study comparing 664,472 autosomal SNPs in 763 long-lived individuals (mean age: 99.7 years) and 1085 controls (mean age: 60.2 years). Top SNPs from the GWAS were further investigated in an independent German sample comprised of 754 long-lived individuals (mean age: 96.9 years) and 860 controls (mean age: 67.3 years).
Conclusions
Thirty-two SNPs previously associated with longevity were not associated with longevity in this study
Indentifier
rs10924270
Reference