LongevityMap Gene

Gene details

HGNC symbol
EEF1AKMT3 
Aliases
FAM119B; METTL21B 
Common name
EEF1A lysine methyltransferase 3 
Description
Cytogenetic Location
12q14.1
UCSC Genome Browser
View 12q14.1 on the UCSC genome browser
OMIM
615258
Ensembl
ENSG00000123427
UniProt/Swiss-Prot
MT21B_HUMAN
Entrez Gene
25895
UniGene
632720
1000 Genomes
1000 Genomes

Homologs in model organisms

Mus musculus
Mettl21b
Rattus norvegicus
LOC679247

Studies (1)

Significant/Non-significant: 1/0

Longevity Association
Significant
Population
American
Study Design
A genome-wide linkage scan was performed for healthy aging in family study data, followed by fine-mapping by association in a separate population. A frailty index, called FI34, was introduced as a quantitative measure of healthy aging.
Conclusions
A single linkage peak was found on chromosome 12 in the genome-wide linkage scan. Fine-scale association mapping identified three sites associated with healthy aging in intergenic regions at 12q13-14.
Indentifier
rs923829
Reference