LongevityMap Gene

Gene details

HGNC symbol
C17orf78 
Aliases
 
Common name
chromosome 17 open reading frame 78 
Description
Cytogenetic Location
17q12
UCSC Genome Browser
View 17q12 on the UCSC genome browser
OMIM
Ensembl
ENSG00000278505
UniProt/Swiss-Prot
CQ078_HUMAN
Entrez Gene
284099
UniGene
439154
1000 Genomes
1000 Genomes

Homologs in model organisms

Mus musculus
Gm11437
Rattus norvegicus
LOC100361746

Studies (1)

Significant/Non-significant: 0/1

Longevity Association
Non-significant
Population
Italian (Southern)
Study Design
A two-stage case-control study was performed to identify the association between longevity and variation of in homeostasis regulation pathway genes. 317 SNPs in 104 genes were analyzed in 78 cases (≥90 years, median age 98 years, 42 females) and 71 controls (<90 years, median age 67 years, 32 females) in stage 1. Then, 31 candidate SNPs identified in stage 1 (π markers = 0.1) were analyzed in an independent sample composed by 288 cases (≥90 years, median age 92 years, 163 females) and 554 controls (<90 years, median age 67 years, 277 females).
Conclusions
After adjustment for multiple testing, no significant association was identified between various SNPs and longevity.
Indentifier
rs829152
Reference